CRYO-ROP PARTICIPATING CENTER - CHICAGO (ILLINOIS EYE AN

Research project

Description

This is an application to become one of the cooperating study centers in
the Cryotherapy for Retinopathy of Prematurity Study. The CRYO-ROP Study
consists of essentially two research components: (1) a clinical trial of
the safety and efficacy of cryotherapy in reducing blindness in eyes with
severe, high risk, ROP; and (2) a study of the natural history (in accord
with the international classification of ROP) of retinopathy in very low
birth weight infants (less than 1251g). In this proposal we document the ability of our group of opthalmologists
and neonatologists to enroll, each year, 213 very low birth weight infants
who have survived for at least 28 days in the natural history study. We
anticipate that 5% of these infants will also develop retinopathy of
prematurity severe enough to become eligible for enrollment of the clinical
trial, and that an additional 25-30 patients per year will be available for
the recruitment period due to expansion of the neonatal limits involved in
the study. The CRYO-ROP Study is chaired by Earl A. Palmer, M.D., at the Oregon Health
Sciences University. The Coordinating Center is directed by Robert J.
Hardy, Ph.D., at the University of Texas Health Sciences Center, Houston.
StatusActive
Effective start/end date9/30/85 → …

Funding

  • National Institutes of Health: $33,000.00

Fingerprint

Retinal Rod Photoreceptor Cells
Tubulin
ROP
Cryotherapy
Natural History
Retinopathy of Prematurity
Very Low Birth Weight Infant
Blindness
Clinical Trials
Safety
Weights and Measures
Health
Research

Keywords

  • Medicine(all)