Center for Innovation and Drug Discovery

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Nicotinamide N-Methyltransferase Chemical Compounds
Narcotic Antagonists Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Hydroxamic Acids Chemical Compounds
delta Opioid Receptor Chemical Compounds
Pharmacokinetics Chemical Compounds
Acetylcholinesterase Medicine & Life Sciences
Amines Medicine & Life Sciences

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Research Output 1993 2018

1 Citations

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Neelakantan, H., Vance, V., Wetzel, M. D., Wang, H. Y. L., McHardy, S. F., Finnerty, C. C., Hommel, J. D. & Watowich, S. J. Jan 1 2018 In : Biochemical Pharmacology. 147, p. 141-152 12 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
High Fat Diet
Nutrition
Obesity
Fats
5 Citations

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

Neelakantan, H., Vance, V., Wang, H. Y. L., McHardy, S. F. & Watowich, S. J. Feb 14 2017 In : Biochemistry. 56, 6, p. 824-832 9 p.

Research output: Contribution to journalArticle

Nicotinamide N-Methyltransferase
Assays
Monitoring
Substrates
Methionine
6 Citations

Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015)

McHardy, S. F., Wang, H. Y. L., McCowen, S. V. & Valdez, M. C. Apr 3 2017 In : Expert Opinion on Therapeutic Patents. 27, 4, p. 455-476 22 p.

Research output: Contribution to journalReview article

Literature
Patents
Cholinesterase Inhibitors
Acetylcholinesterase
Organophosphates