Center for Innovation and Drug Discovery

Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Narcotic Antagonists Medicine & Life Sciences
Structure-Activity Relationship Medicine & Life Sciences
Amines Medicine & Life Sciences
Nicotinamide N-Methyltransferase Chemical Compounds
Hydroxamic Acids Chemical Compounds
delta Opioid Receptor Chemical Compounds
Pharmacokinetics Chemical Compounds
Derivatives Chemical Compounds

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Research Output 1993 2018

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Neelakantan, H., Vance, V., Wetzel, M. D., Wang, H. Y. L., McHardy, S. F., Finnerty, C. C., Hommel, J. D. & Watowich, S. J. Jan 1 2018 In : Biochemical Pharmacology. 147, p. 141-152 12 p.

Research output: Research - peer-reviewArticle

Nicotinamide N-Methyltransferase
Nutrition
Fats
Membranes
Molecules
2 Citations

Noncoupled Fluorescent Assay for Direct Real-Time Monitoring of Nicotinamide N-Methyltransferase Activity

Neelakantan, H., Vance, V., Wang, H. Y. L., McHardy, S. F. & Watowich, S. J. Feb 14 2017 In : Biochemistry. 56, 6, p. 824-832 9 p.

Research output: Research - peer-reviewArticle

Nicotinamide N-Methyltransferase
Assays
Monitoring
Substrates
Methionine
4 Citations

Recent advances in acetylcholinesterase Inhibitors and Reactivators: an update on the patent literature (2012-2015)

McHardy, S. F., Wang, H. Y. L., McCowen, S. V. & Valdez, M. C. Apr 3 2017 In : Expert Opinion on Therapeutic Patents. 27, 4, p. 455-476 22 p.

Research output: Research - peer-reviewReview article

Literature
Patents
Cholinesterase Inhibitors
Acetylcholinesterase
Ligands